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In obstructive snooze apnea (OSA), doses as much as 250 mg/day happen to be very well-tolerated but there is no dependable proof of further advantage outside of the 150 mg/day.ceritinib will improve the level or result of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.modafinil will reduce the extent or impact